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New study aims to uncover hidden dangers of shingles virus in the brain

NCT ID NCT07554261

Knowledge-focused Sponsor: Kocaeli University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study looks back at medical records of 50 adults who had a shingles virus infection in their brain or spinal cord. Researchers want to find out what makes some people more likely to get these serious infections and what leads to long-term problems like memory loss or seizures. The goal is to better understand the disease so doctors can improve care and outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (≥18 years) diagnosed with varicella zoster virus (VZV)-related central nervous system infections, including meningitis and encephalitis, identified from participating centers. Patients are included based on molecular confirmation of VZV in cerebrospinal fluid and availability of clinical follow-up data.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age ≥18 years Molecular confirmation of VZV (PCR-Polymerase Chain Reaction) in CSF fluid Diagnosis of meningitis or encephalitis Exclusion Criteria: Missing key clinical data Inadequate follow-up

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Conditions

The condition(s) this trial relates to.

Encephalitis, Varicella Zoster varicella zoster infection Varicella Zoster Virus Infection viral meningitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Varicella encephalitis Varicella meningitis Varicella neurological Varicella zoster

Contacts and locations

Locations

  • Kocaeli University

    İzmit, Kocaeli, 41380, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.