New hope for thyroid eye disease: drug safety trial underway

NCT ID NCT06812325

Ongoing Disease control Sponsor: Viridian Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jan 07, 2026 · Last updated May 19, 2026 · Updated 19 times

Summary

This study tests a new drug called VRDN-003 for people with Thyroid Eye Disease (TED), a condition that can cause bulging eyes and discomfort. The main goal is to check the drug's safety and side effects over 24 weeks. About 321 participants will receive either the drug or a placebo to see if it helps control the disease without needing long-term medication.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abeillon du Payrat

Bron, 69500, France
Addenbrookes Hospital

Cambridge, United Kingdom
Advanced Quality Medical Research

Orland Park, Illinois, 60462, United States
Akdeniz Üniversitesi Tıp Fakültesi Göz Hastalıkları Anabilim Dalı

Antalya, 07059, Turkey (Türkiye)
Alfa Medical Research

Davie, Florida, 33024, United States
C A Clinical Trial Corp.

Cape Coral, Florida, 33990, United States
California Eye Specialists Medical Group INC

Pasadena, California, 91107, United States
Catalina Eye Care

Tuscon, Arizona, 85712, United States
Centrum Medyczne Pratia Gdynia

Gdynia, 81-338, Poland
Centrum Medyczne Pulawska Sp. z o.o.

Piaseczno, 05-500, Poland
Charite Universitatsmeizin Berlin KoR Campus Virchow Klinikum

Berlin, Germany
Clinica Universidad de Navarre

Navarrés, Spain
Continental Clinical Research

Miami, Florida, 33144, United States
D H Doral Research Center

Doral, Florida, 33132, United States
DFW Clinical Trials

Carrollton, Texas, 75010, United States
ETG Lublin

Lublin, 20-412, Poland
East Coast Institute for Research, LLC

Jacksonville, Florida, 32216, United States
Edward Jenner Research Group LLC

Plantation, Florida, 33317, United States
Elevate Clinical Research

Seabrook, Texas, 77586, United States
Eye Centers of Florida

Fort Myers, Florida, 33901, United States
Eyeplastx

San Antonio, Texas, 78258, United States
FOMAT Medical Research

Pismo Beach, California, 93030, United States
Fraser Eye Care Center

Fraser, Michigan, 48026, United States
Gazi University Medical Faculty Hospital

Ankara, Turkey (Türkiye)
Guy's and St Thomas' NHS Foundation Trust

London, SE1 7EH, United Kingdom
Hacettepe Univeristy Medical Fculty Hospital

Ankara, Turkey (Türkiye)
Herco Medical and Research Center

Coral Gables, Florida, 33134, United States
Hospital La Arruzafa

Córdoba, 14012, Spain
Hospital Provincial de Conxo

A Coruña, 15706, Spain
Hospital Universitario Miguel Servet Consultas de Oftalmologia

Zaragoza, Spain
Hospital Universitario Ramon y Cajal

Madrid, 28034, Spain
Hospital Universitario Virgen Macarena

Seville, 41009, Spain
Hôpital La Pitiélsalpêtrière

Paris, France
Imperial College Healthcare NHS Trust

London, NW1 5QH, United Kingdom
Institut Català de Retina

Barcelona, 08017, Spain
Jackson Clinic

Jackson, Tennessee, 38305, United States
Johannes Gutenberg University Medical Center Department of Medicine 1

Mainz, Germany
Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi Göz Hastalıkları Kliniği

Istanbul, Turkey (Türkiye)
Mayo Clinic Rochester

Rochester, Minnesota, 55905, United States
Moorefields Eye Hospital NHS Foundation Trust

London, United Kingdom
Neuro Eye Clinical Trials

Houston, Texas, 77074, United States
Ophthalmic Consultants of Boston

East Weymouth, Massachusetts, 02189, United States
Optimum Profesorskie Centrum Okulistyki Sp. z o. o.

Gdansk, 80-180, Poland
Orbital Plastics

Newport Beach, California, 92660, United States
Pacific Neuroscience Institute

Santa Monica, California, 90404, United States
Pacific Neuroscience Institute at Saint John's Physician Partners

Torrance, California, 90503, United States
Pioneer Research Solutions Inc.

Houston, Texas, 77099, United States
Polimedica PTG

Warsaw, 02-777, Poland
Retreat Medical Research

Miami, Florida, 33135, United States
Rutgers New Jersey Medical School

Newark, New Jersey, 07103, United States
San Antonio Clinical Trials

San Antonio, Texas, 78240, United States
Santa Familia PTG Lodz

Lodz, 90-302, Poland
Sarasota Retina Institute

Sarasota, Florida, 34239, United States
Servicde d'Endocrinologie, Diabetologieet Nutrition Centre Hospitalier Universitaire d'Angers

Angers, France
Sina Medical Center

Homestead, Florida, 33034, United States
Southern Clinical Research LLC

Miami, Florida, 33125, United States
The Newcastle Upon Tyne Hospitals NHS Foundation Trust

Newcastle, United Kingdom
United Medical Research Institute

Inglewood, California, 90301, United States
Universitaetsmedizin Goettingen

Göttingen, 37075, Germany
Universitatsklinikum Essen

Essen, Germany
University Hospitals Bristol and Weston NHS Foundation Trust Clinical Research Unit

Bristol, United Kingdom
University of Missouri Kansas City

Kansas City, Missouri, 64108, United States
Uniwersytecki Szpital Kliniczny w Białymstoku, Klinika Okulistyki, Centrum Badań Klinicznych

Bialystok, 15-276, Poland
Warszawski Szpital Okulistyczny

Warsaw, 01-258, Poland

Conditions

Explore the condition pages connected to this study.

THYROID EYE DISEASE, TED