Virtual reality takes on alcohol addiction: a new weapon against relapse?
NCT ID NCT05841823
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether virtual reality exposure therapy (VRET) can help men with alcohol use disorder reduce their psychological dependence on alcohol and prevent relapse. Eighty men who have completed detox will be randomly assigned to either VRET or standard treatment. VRET uses relaxing scenes and personalized high-risk situations (like a bar or home setting) with associated smells to help patients practice coping with cravings. The study will track changes in drinking behavior, cravings, and withdrawal symptoms over six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- virtual reality exposure therapy
- What this could lead to
- If effective, virtual reality could become a new, drug-free tool to help people with alcohol use disorder manage cravings and stay sober.
- What could go wrong
- This is a small, early-stage trial with 80 participants, so results may not apply to everyone. The therapy's long-term benefits are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Jun 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Hospitalized patients diagnosed with alcohol use disorder (confirmed by the relevant diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders-V). 2. Male, age 18 to 55 years old, Han nationality, junior high school education or above, right-handed (because of the difference in EEG between right-hand and left-hand). 3. Those with normal eyesight (including corrected vision). Exclusion Criteria: 1. Those with current and lifetime history of abuse of any other psychoactive substances (except tobacco). 2. Those with current and lifetime history of other mental diseases. 3. Those with current and lifetime history of central nervous system diseases or serious physical illnesses. 4. Those who are unable to complete the EEG detection or psychological scale assessment. 5. Those who are unable to cooperate with ACT or VRET, or who are seriously uncomfortable with psychotherapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Second Affiliated Hospital of Henan Medical University
Xinxiang, Henan, 453000, China
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