Virtual reality could revolutionize how we measure vision loss
NCT ID NCT07433088
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to see if virtual reality tests can better measure how age-related macular degeneration affects daily life compared to standard eye exams. Researchers will enroll 60 participants, including healthy adults and those with the eye condition. The goal is to develop a more accurate way to assess functional vision in real-world situations.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 50 years * Sufficient knowledge of the French language * Ability to give personal, express, free, and informed consent * Ability to comply with the requirements of the protocol * Person covered by Social Security * Clarity of the ocular environment, adequate pupil dilation to allow the collection of good quality images, as determined by the investigator Additional inclusion criteria for group 1, healthy subjects: * No detectable visual pathologies * Best monocular visual acuity ≥ 8/10 Additional inclusion criteria for group 2, subjects with LMA, early AMD, or intermediate AMD without atrophy: * Diagnosis of AMD, early AMD, or intermediate AMD * Absence of geographic atrophy * Presence of drusen (diameter \> 63 µm) with or without pigmentary changes Additional inclusion criteria for group 3, subjects with dry AMD with perifoveal atrophy: * Diagnosis of atrophic AMD * Presence of drusen (diameter \> 125 µm) * Location of geographic atrophy as determined by the investigator: extrafoveal, juxtafoveal * Preservation of central vision confirmed by the investigator based on a comprehensive and integrated interpretation of SD-OCT, FAF, retinography, and best corrected visual acuity examinations. Additional inclusion criteria for group 4, Subject with dry AMD with foveal atrophy: * Diagnosis of atrophic AMD * Presence of drusen (diameter \> 125 µm) * Investigator's localization of geographic atrophy: retrofoveal * Central vision impairment confirmed by the investigator based on a comprehensive and integrated interpretation of SD-OCT, FAF, retinography, and best corrected visual acuity examinations. Exclusion Criteria: * Pregnant women, women in labor, or breastfeeding women * Subjects undergoing drug treatments that may cause motor, visual, vestibular, or cognitive disorders (PSA, neuroleptics, etc.) or that could interfere with the study examinations * Any concomitant intraocular condition in the eye being studied (e.g., glaucoma or cataract) * Any retinal pathology that could cause retinal atrophy other than AMD (eliminate dystrophy, chronic CRSC, pachyatrophy, resorption of vitelliform material with atrophy, high myopia, etc.) * Known systemic disease that, in the investigator's opinion, would prevent active participation in the study * Participation in any other therapeutic study evaluating a drug. * Subjects with cognitive impairment, illiterate subjects, and subjects who do not speak the national language. * Persons subject to enhanced protection or legal safeguards (guardianship, trusteeship).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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