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Mind over paralysis: can thinking about walking reboot the brain?

NCT ID NCT07732868

Knowledge-focused Sponsor: José Gabriel da Silva Figueiredo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study tests whether a virtual reality brain-machine interface can help people with spinal cord injury regain function. Participants imagine moving their legs while wearing an EEG cap and VR headset, receiving sensory feedback. The goal is to understand how the brain's communication patterns change during this therapy and whether those changes relate to real-world improvement.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a virtual reality-based brain-machine interface protocol with sensory feedback and optional exoskeleton
What this could lead to
If it works, this could point toward a new rehabilitation approach for spinal cord injury that harnesses the brain's ability to adapt.
What could go wrong
This is a very early, small study with only 20 participants. It focuses on measuring brain changes, not on proving clinical improvement, so the rehabilitation benefits remain uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Any gender * Age between 18 and 65 * Able to follow instructions and communicate verbally in Portuguese (or english for able bodied volunteers) * For the spinal cord injury group: * American Spinal Injury Association - ASIA - Impairment Scale (AIS) grade A, B, or C * Traumatic * Subacute condition * With upper limb dexterity to manipulate virtual reality controlers Exclusion Criteria: * Pregnant/breastfeeding women * Disability/neurological condition that may interfere with tasks or measurements (e.g., cognitive impairment, dementia, brain injury) * Physical injury that prevents the use of the equipment (e.g., limb amputation) * History of severe psychiatric illness * Inability to decide autonomously * Conditioned binocular vision * Photosensitive epilepsy

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Conditions

The condition(s) this trial relates to.

paraplegia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Able bodied Paraplegia, spinal Spinal cord injury Traumatic spinal cord injuries

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centro de Reabilitação do Norte (CRN) Dr. Ferreira Alves, Unidade Local de Saúde de Gaia/Espinho

    Vila Nova de Gaia, 4405-565, Portugal

  • Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro

    Aveiro, 3810-193, Portugal

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