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New drug shows promise for slowing kidney damage in alport syndrome

NCT ID NCT06425055

First seen Feb 10, 2026 · Last updated May 22, 2026 · Updated 11 times

Summary

This study tested a drug called vonafexor in 26 people with Alport syndrome, a genetic condition that harms the kidneys. The goal was to see if the drug is safe and can help protect kidney function. Researchers measured side effects and changes in kidney health over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dr Anjay Rastogi - UCLA Health, David Geffen School of Medicine

    Los Angeles, California, 90095, United States

  • Dr Ankit Mehta - Renal Disease Research Institute

    Dallas, Texas, 75126, United States

  • Dr Arnold Silva - Boise Kidney & Hypertension

    Boise, Idaho, 83703, United States

  • Dr Eric Wallace - University of Alabama

    Birmingham, Alabama, 35294, United States

  • Dr James Simon - Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Dr Moglie Le Quintrec - Hopital Lapeyronie

    Montpellier, 34090, France

  • Dr Suneel Udani - NANI Research

    Hinsdale, Illinois, 60521, United States

  • Dr Tingting Li - Washington University

    St Louis, Missouri, 63110, United States

  • Fundacio Puigvert

    Barcelona, 08025, Spain

  • Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • Hospital Virgen de la Arrixaca

    El Palmar, 30120, Spain

  • Pr Claire Rigothier - CHU De Bordeaux

    Bordeaux, 33076, France

  • Pr. Bertrand Knebelmann - Necker Enfants Malades

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.