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New study tracks voice recovery after throat surgery

NCT ID NCT07579364

Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 500 adults with vocal cord paralysis or atrophy who undergo laryngeal framework surgery. Researchers will track voice quality, swallowing ability, and complication rates for two years after surgery. The goal is to understand which surgical techniques work best for different patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help surgeons choose the best surgical technique for each patient, improving voice quality and reducing complications.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Potential participants will be identified by treating laryngologists at the lead site (UCSF) or partner sites (Massachusetts Eye and Ear, Wake Forest, University of Cincinnati, UCSD) at the time the patient presents for their visit. If the patient is determined to have UVFP or vocal fold atrophy and is interested in undergoing surgical treatment, they will be asked about their interest in participating.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Over 18 years of age * Diagnosed UVFP or VFA * English speaking * willing and able to follow up for 2 years Exclusion Criteria: * under 18 * non-English speaking

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Conditions

The condition(s) this trial relates to.

congenital laryngeal palsy Vocal Cord Paralysis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Unilateral vocal cord paralysis Vocal cord atrophy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    10 sites. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Massachusetts Eye and Ear Infirmary

    Boston, Massachusetts, 02114, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • University of California, San Diego

    La Jolla, California, 92093, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • Wake Forest University

    Winston-Salem, North Carolina, 27101, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.