Can a voice test prevent vocal cord damage?
NCT ID NCT05625191
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how voice sounds change when people strain their vocal cords. Researchers will measure specific voice features in 100 adults, some with and some without vocal cord injury. The goal is to find early warning signs that could help prevent voice damage before it happens.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients (18-65 years of age) with a diagnosis of phonotrauma will be recruited from the laryngology clinics at UTSW Voice Center. All patients who are diagnosed with phonotraumatic vocal fold lesions (including vocal fold nodules, phonotraumatic polyps, mid-fold edema, and pseudocysts) will be referred for enrollment. Individuals without phonotrauma (18-65 years of age) will be recruited for the control group.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Control Group: Inclusion Criteria: 1. 18-65 years of age (to avoid confounding physiological factors related to puberty or presbyphonia) 2. No history of or current voice disorder 3. Auditory perceptual presentation globally within functional limits (as determined by a voice specialized SLP). Exclusion Criteria: 1. Atypical auditory-perceptual voice presentation 2. History of voice disorder or laryngeal surgery. Patient Group: Inclusion Criteria: 1. Diagnosed with phonotrauma (i.e., vocal fold nodules, vocal fold polyp, vocal fold pseudocyst, mid-fold edema) by a laryngologist. 2. 18-65 years of age Exclusion Criteria: 1. Diagnosis of voice disorder not related to phonotrauma (e.g., vocal fold immobility, laryngeal dystonia, primary muscle tension dysphonia, etc.) 2. Previous history of laryngeal surgery or voice therapy (to avoid confounding effects of previous treatment).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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Contacts and locations
Locations
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75235, United States
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