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Nerve stimulation plus exercise shows promise for spinal cord recovery

NCT ID NCT06351111

First seen Nov 03, 2025 · Last updated Jun 21, 2026 · Updated 36 times

Summary

This study tests whether stimulating the vagus nerve during rehabilitation exercises can help people with chronic spinal cord injury regain movement and sensation. Twenty participants who completed an earlier trial will receive active VNS paired with exercises targeting hand, leg, bladder, or sensory function. The main goal is to check safety, with secondary goals of measuring improvements in function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor University Medical Center

    Dallas, Texas, 75246, United States

  • Texas Biomedical Device Center

    Richardson, Texas, 75080, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vagus nerve stimulation (VNS) device paired with rehabilitation exercises

What this could lead to

If successful, this could point toward a way to improve hand, leg, bladder, and sensory function in people with chronic spinal cord injury.

What could go wrong

This is a small, early-stage follow-on study with only 20 participants, so results may not apply to everyone. The main goal is safety, and it's unclear how much function can be restored.

Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.