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New pill takes on Virus-Linked lymphoma in early trial

NCT ID NCT06789159

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 40 times

Summary

This early-phase trial tests an oral drug called VK-2019 in 30 adults with a type of lymphoma (DLBCL) that is linked to the Epstein-Barr virus and has not responded to at least two prior treatments. Participants will take one of three daily doses (600, 1200, or 1800 mg) in 28-day cycles. The main goal is to find the safest dose and check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kentucky

    Lexington, Kentucky, 40506, United States

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VK-2019 (an oral drug)

What this could lead to

If it works, this could point toward a new treatment option for people with a hard-to-treat type of lymphoma linked to the Epstein-Barr virus.

What could go wrong

This is a very early Phase Ib trial with only 30 people, focused on safety and dosing. It may not show enough benefit to move forward, and side effects are unknown.

Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma Epstein-Barr virus infection Infections relapsed/refractory diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.