New cream aims to stop vitiligo relapse after repigmentation
NCT ID NCT06446063
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tested a cosmetic cream called RV5098A to see if it could help adults with vitiligo keep their facial pigmentation after successful repigmentation treatment. Vitiligo causes white patches on the skin, and even after treatment, about 40% of people lose color again within a year. The study enrolled 19 participants who applied the cream twice daily to their entire face. However, the trial was terminated early, so we have limited data on whether it works.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- RV5098A (a cosmetic cream)
- What this could lead to
- If it works, this could help people with vitiligo keep their skin color longer after repigmentation treatment.
- What could go wrong
- The trial was terminated early with only 19 participants, so results are limited. It is a cosmetic product, not a drug, and may not provide lasting benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
19 people
The number who actually took part.
- Started
-
May 2024
- Finished
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Oct 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects will be enrolled from the investigator's outpatient's reception and/or from the database of the centre. The subjects corresponding to eligibility criteria may receive a phone call, a letter or an e-mail proposing to participate to the clinical study.
- Ages
-
18 to 75 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Criteria related to the population: \- Subject aged between 18 and 75 years included. Criteria related to the disease: * Subject with facial vitiligo, regardless of its duration. * having a sufficient repigmentation rate of the vitiligo after repigmenting treatment Criteria related to treatments and/or products: \- Subject responder to a repigmenting treatment Non-inclusion Criteria: Criteria related to the diseases / skin condition: * Subject with active vitiligo. * Subject with spontaneous repigmentation without treatment. * Subject having other dermatological condition, an acute, chronic, or progressive disease or history of disease liable to interfere with the study assessments or considered by the Investigator hazardous for the subject or incompatible with the study requirements. Criteria related to treatments and/or products: * Systemic immunomodulatory treatment taken for another pathology, before inclusion, on-going or planned to be established during the study. * Any topical immunomodulatory treatment applied on the face for another pathology, on-going or planned to be established during the study. * Any other topical or systemic treatment established or modified during the previous weeks or planned to be established or modified during the study, liable to interfere with the evaluation of the efficacy according to the investigator's assessment. * Any dietary supplement for vitiligo within 4 weeks before the inclusion visit or planned to be established during the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
COSDERMA
Bordeaux, Gironde, 33000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a skin cream bring back color to faces with vitiligo?
- Skin markers may reveal how light therapy fights vitiligo
- Can Real-World data unlock better skin disease care?
- New ointment aims to restore skin color in vitiligo
- Skin microbes linked to vitiligo and immunotherapy reactions in melanoma patients
- New vitiligo registry aims to uncover disease trends in 2,500 patients