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Vitamin e and fiber combo tested for cholesterol control
NCT ID NCT07610304
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether taking vitamin E (400 mg daily) alone or together with psyllium husk (10 g daily) for 60 days could improve blood fat levels in adults with high cholesterol and triglycerides. Sixty participants aged 40–60 were randomly assigned to one of three groups: vitamin E alone, vitamin E plus psyllium, or a placebo. Researchers measured changes in cholesterol and triglycerides at 30 and 60 days to see if either supplement combination made a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin E (alpha tocopherol) and psyllium husk (dietary fibre)
- What this could lead to
- If it works, this could point toward a simple, low-cost dietary supplement approach to help manage cholesterol and triglyceride levels.
- What could go wrong
- This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. Dietary supplements often have modest effects and are not a substitute for standard medications like statins.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
60 people
The number who actually took part.
- Started
-
Jun 2022
- Finished
-
Aug 2022
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants' age is between 40 to 60 years * Total cholesterol ≥200 mg/dL and * Triglycerides ≥150 mg/dL * Not receiving lipid-lowering therapy Exclusion Criteria: Participants were excluded from the study if they: * Had any other non-communicable disease (e.g. uncontrolled diabetes, cardiovascular disease, or chronic kidney disease) * Were using statins, fibrates, beta-blockers, or antioxidant supplements * Had Familial hyperlipidemia
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tertiary medical centres: Fatima Memorial Hospital, Services Hospital and National Hospital
Lahore, Pakistan
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