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Does vitamin d boost IVF success? new study investigates

NCT ID NCT02361827

Knowledge-focused Sponsor: The First Affiliated Hospital of Zhengzhou University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether vitamin D levels in the blood affect the chance of a successful pregnancy after in vitro fertilization (IVF). Researchers followed 688 women aged 21-40 undergoing their first IVF cycle. The goal was to see if women with higher vitamin D levels had higher ongoing pregnancy rates at 12 weeks. The results could help clarify a controversial topic, but because this is an observational study, it cannot prove that vitamin D directly improves IVF outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a clear link is found, it could help doctors advise women on vitamin D levels before IVF to possibly improve pregnancy chances.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Previous studies have had conflicting results, and this one may not settle the debate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

688 people

The number who actually took part.

Started

Jan 2018

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients whose IVF cycles were cancelled due to ovarian hyperstimulation syndrome were also excluded);.

Ages

21 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. age between 21-40 years old 2. basal FSH hormone level less than 10 mIU/mL 3. the first cycle of IVF treatment with standard long protocol 4. both ovarian present and normal uterus. Exclusion Criteria: 1. Important data missing 2. Gametes donation cycles 3. Anyone that does not meet the inclusion criteria

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Conditions

The condition(s) this trial relates to.

vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

In vitro fertilization Ongoing pregnancy rate Vitamin D

Contacts and locations

Locations

  • Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.