AI crystal ball for hospital wards: can software forecast oxygen drops 24 hours early?
NCT ID NCT07742813
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This trial tests whether an AI software called Vital-PICASO can predict if a hospital patient will develop hypoxia—dangerously low blood oxygen—within the next 24 hours. Using vital signs like heart rate, blood pressure, and oxygen levels from 2,250 adult patients, the software generates a risk score. Researchers compare these scores against actual hypoxia events to see if the AI is accurate enough to serve as an early warning system in general wards.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vital-PICASO, an AI-based software that analyzes vital signs to predict hypoxia risk
- What this could lead to
- If it works, this AI tool could give hospital staff an early warning system, helping them spot patients at risk of low oxygen levels a day in advance and potentially preventing emergencies.
- What could go wrong
- This is a retrospective study using existing medical records, not a live test, so real-world performance may differ. The software's predictions are compared against a set threshold, and it may not work equally well for all patients or hospital settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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2,250 people
The number who actually took part.
- Started
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Aug 2025
- Finished
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Jul 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of male and female patients aged 19 years or older who were admitted to a general ward at Seoul National University Hospital for at least 12 hours and had electronic medical record data available between January 1, 2023, and May 31, 2025. The retrospective study datasets include hypoxia-positive and hypoxia-negative cases evaluated separately according to two reference-standard criteria: oxygen saturation below 94% and oxygen administration at a flow rate of 4 L/min or more.
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: General Criteria * Male or female patient aged 19 years or older at the time the clinical data were recorded * Electronic medical record data available between January 1, 2023, and May 31, 2025 * Admission to a general ward for at least 12 hours * Clinical data not previously used in the development of Vital-PICASO SpO2-Based Hypoxia-Positive Group * Hypoxia occurred in a general ward * Hypoxia was defined as oxygen saturation below 94% * Vital-sign data were available for up to 72 hours before the hypoxia event * If hypoxia occurred within 24 hours after admission or transfer to the general ward, all available vital-sign data recorded before the event were included * If multiple eligible hypoxia events occurred during the data collection period, only the first eligible event was included for this criterion SpO2-Based Hypoxia-Negative Group * No hypoxia occurred during the selected general ward admission * Data were randomly selected from the same general wards as the corresponding hypoxia-positive group * Vital-sign data were available from a time interval comparable with the hypoxia-event reference time or for up to 72 hours after admission to the general ward * Only one eligible data interval was included per patient Oxygen-Treatment-Based Hypoxia-Positive Group * Hypoxia occurred in a general ward * Hypoxia was defined as oxygen administration at a flow rate of 4 L/min or more * Vital-sign data were available for up to 72 hours before the initiation of oxygen administration * If oxygen administration began within 24 hours after admission or transfer to the general ward, all available vital-sign data recorded before the event were included * If multiple eligible events occurred during the data collection period, only the first eligible event was included for this criterion Oxygen-Treatment-Based Hypoxia-Negative Group * No hypoxia occurred during the selected general ward admission * Data were randomly selected from the same general wards as the corresponding hypoxia-positive group * Vital-sign data were available from a time interval comparable with the hypoxia-event reference time or for up to 72 hours after admission to the general ward * Only one eligible data interval was included per patient Exclusion Criteria: * Hypoxia occurred outside a general ward * The patient had chronic obstructive pulmonary disease * A do-not-resuscitate order was in effect at the time the clinical data were recorded * The patient was pregnant or within 3 months after delivery at the time the clinical data were recorded * The data were considered inappropriate for the study by the principal investigator
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Seoul National University Hospital
Seoul, South Korea
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