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New drug aims to reverse wasting in cancer patients

NCT ID NCT07112196

Symptom relief Sponsor: CatalYm GmbH Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 01, 2026 · Updated 6 times

Summary

This study tests a new drug called visugromab in about 518 people with advanced cancer who are losing weight unintentionally (cachexia). The goal is to see if the drug helps them regain weight, improve appetite, and move better compared to a placebo. Participants receive the drug or placebo as a drip every 4 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2/3

Runs two stages together: whether the treatment works, then large-scale confirmation.

Participants

About 518 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Weight loss * Advanced cancer Exclusion Criteria: * Participation in another interventional clinical trial, receipt of any investigational therapy or use of any investigational device within 4 weeks prior to screening and between screening and the first dose of investigational product

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Get notified about this study

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Conditions

The condition(s) this trial relates to.

Anorexia Cachexia neoplasm Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer-associated cachexia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    71 sites in 12 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • AP-HP Hôpital Henri Mondor

    RECRUITING

    Créteil, 94010, France

  • ASST degli Spedali Civili di Brescia

    RECRUITING

    Brescia, 25123, Italy

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, CB2 0RE, United Kingdom

  • Akershus University Hospital

    RECRUITING

    Oslo, 1478, Norway

  • Astera Cancer Care

    RECRUITING

    East Brunswick, New Jersey, 08816, United States

  • Augusta University Medical Center

    RECRUITING

    Augusta, Georgia, 30912, United States

  • Azienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant'Anna

    RECRUITING

    Ferrara, 44124, Italy

  • CHRU de Brest - Hopital Morvan

    RECRUITING

    Brest, 29200, France

  • Cantonal Hospital St. Gallen (Kantonsspital St. Gallen)

    RECRUITING

    Sankt Gallen, 9000, Switzerland

  • Centre Paul Strauss

    RECRUITING

    Strasbourg, 67200, France

  • Centro Ricerche Cliniche di Verona

    RECRUITING

    Verona, 37134, Italy

  • Centro Riferimento Oncologico - Aviano

    RECRUITING

    Aviano, 33081, Italy

  • Clermont Oncology Center

    RECRUITING

    Clermont, Florida, 34711, United States

  • Cleveland Clinic (Main Campus)

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Cleveland Clinic Avon Hospital

    RECRUITING

    Avon, Ohio, 44011, United States

  • Cleveland Clinic Fairview Hospital

    RECRUITING

    Fairview, Ohio, 44111, United States

  • Cleveland Clinic Hillcrest Hospital

    RECRUITING

    Mayfield Heights, Ohio, 44124, United States

  • Cleveland Clinic Martin Health

    RECRUITING

    Stuart, Florida, 34994, United States

  • Complex Oncology Center - Vratsa EOOD

    RECRUITING

    Vratsa, 3001, Bulgaria

  • Eastern Connecticut Hematology & Oncology

    RECRUITING

    Norwich, Connecticut, 06360, United States

  • Fakultni nemocnice Hradec Kralove

    RECRUITING

    Hradec Králové, 500 05, Czechia

  • Fakultni nemocnice v Motole

    RECRUITING

    Prague, 15006, Czechia

  • Freeman Hospital

    RECRUITING

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • FutureMeds Krakow

    RECRUITING

    Krakow, 31-501, Poland

  • FutureMeds Sp.zo.o - FutureMeds Wrocław

    RECRUITING

    Wroclaw, 53-673, Poland

  • FutureMeds Targówek

    RECRUITING

    Warsaw, 03-505, Poland

  • Futuremeds Hospital Viamed Santa Elena

    RECRUITING

    Madrid, 28003, Spain

  • Futuremeds Romania Brasov

    RECRUITING

    Brasov, 500052, Romania

  • Futuremeds Romania Galati

    RECRUITING

    Galati, 800001, Romania

  • Futuremeds Łódź

    RECRUITING

    Lodz, 91-363, Poland

  • Gral Medical - Oncofort Hospital Pitesti

    RECRUITING

    Piteşti, 110283, Romania

  • Gruppo Ospedaliero Moncucco - Clinica Moncucco

    RECRUITING

    Lugano, 6900, Switzerland

  • HCL Centre Hospitalier Lyon Sud

    RECRUITING

    Lyon, 69495, France

  • Haukeland University Hospital

    RECRUITING

    Bergen, 5009, Norway

  • Hospital Clinic Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital Universitario Puerta de Hierro

    RECRUITING

    Majadahonda, 28222, Spain

  • IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST S.r.l.

    RECRUITING

    Meldola, 47014, Italy

  • Istituto Oncologico della Svizzera Italiana

    RECRUITING

    Bellinzona, 6500, Switzerland

  • Jagiellońskie Centrum Innowacji Sp. z o.o.

    RECRUITING

    Krakow, 30-348, Poland

  • Johanniter Krankenhaus Bonn

    RECRUITING

    Bonn, 53113, Germany

  • Léon Bérard Center (Centre Léon Bérard)

    RECRUITING

    Lyon, 69008, France

  • MS CLINSEARCH Specjalistyczny NZOZ Janusz Milanowski, Katarzyna Szmygin - Milanowska Sp. j.

    RECRUITING

    Lublin, 20-064, Poland

  • Medical Centre Futuremeds Plovdiv

    RECRUITING

    Plovdiv, 4000, Bulgaria

  • Mid Florida Hematology and Oncology Centers

    RECRUITING

    Orange City, Florida, 32763, United States

  • Muenchen Klinik Neuperlach

    RECRUITING

    München, 81737, Germany

  • Multiscan, s.r.o., Nemocnice Horovice

    RECRUITING

    Hořovice, 268 01, Czechia

  • Ninewells Hospital

    RECRUITING

    Dundee, DD2 1SG, United Kingdom

  • Oncolab Craiova

    RECRUITING

    Craiova, 200385, Romania

  • Oncomed S.R.L.

    RECRUITING

    Timișoara, 300239, Romania

  • Oslo University Hospital

    RECRUITING

    Oslo, 0372, Norway

  • Ovidius Clinical Hospital

    RECRUITING

    Ovidiu, 905900, Romania

  • Pratia MCM Kraków

    RECRUITING

    Krakow, 30-727, Poland

  • Pratia Onkologia Katowice

    RECRUITING

    Katowice, 40-519, Poland

  • Pratia Onkologia Wrocław

    RECRUITING

    Wroclaw, 50-019, Poland

  • Royal Surrey County Hospital

    RECRUITING

    Guildford, GU2 7XX, United Kingdom

  • Royal Sussex County Hospital

    RECRUITING

    Brighton, BN2 5BE, United Kingdom

  • Sorlandet sykehus HF - Kristiansand

    RECRUITING

    Kristiansand, 4615, Norway

  • Specialized Hospital for Active Treatment in Oncology

    RECRUITING

    Haskovo, 6300, Bulgaria

  • Spitalul Pelican Oradea

    RECRUITING

    Oradea, 410450, Romania

  • St. Nectarie Oncology Center, Craiova

    RECRUITING

    Craiova, 200801, Romania

  • St. Olavs hospital HF, Universitetssykehuset i Trondheim

    RECRUITING

    Trondheim, 7030, Norway

  • Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie

    RECRUITING

    Krakow, 31-826, Poland

  • The Christie

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • Tumor Zentrum Aarau

    RECRUITING

    Aarau, 5000, Switzerland

  • Universitaetsspital Basel

    RECRUITING

    Basel, 4031, Switzerland

  • University Hospital Carl Gustav Carus Dresden (Universitätsklinikum Carl Gustav Carus Dresden)

    RECRUITING

    Dresden, 01307, Germany

  • University Hospital of A Coruña (Hospital Universitario de A Coruña)

    RECRUITING

    A Coruña, 15006, Spain

  • University Hospital of Zurich (Universitätsspital Zürich)

    RECRUITING

    Zurich, 8006, Switzerland

  • University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna-ISUL

    RECRUITING

    Sofia, 1527, Bulgaria

  • Vseobecna fakultni nemocnice v Praze

    RECRUITING

    Prague, 12808, Czechia

  • Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi.

    RECRUITING

    Lodz, 93-513, Poland