VR eye workouts could help people with eye nerve damage move their eyes better
NCT ID NCT06417216
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether doing eye exercises in virtual reality can help people with certain eye nerve palsies move their eyes more. The VR scene moves with the person's head while they do visual tasks. The goal is to see if this improves eye movement range. The study involves 40 participants with abducens palsy or internuclear ophthalmoplegia.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- head-cancelled virtual reality
- What this could lead to
- If it works, this could offer a new, non-invasive way to improve eye movement in people with certain nerve palsies.
- What could go wrong
- This is a small, early-stage study with only 40 participants. It may not show significant improvement, and results may not apply to all types of eye nerve palsy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
OCNP Group Inclusion Criteria: * Presence of OCNP in one eye with 50% range-of-motion limitation or worse * Able to provide informed consent and will be able to fluently read and understand spoken English OCNP Group Exclusion Criteria: * Presence of bilateral OCNP * Range of motion better than 50% * Visual acuity worse than 20/100 in either eye * Greater than 4-line difference in visual acuity between the eyes, * Structural anomalies or sensory sensitivities (e.g. visual motion sensitivity) that would prevent them from wearing or tolerating a VR headset Participants will be excluded if they are unable to participate if inclusion criteria are not met. Normal Group Inclusion Criteria: * Absence of OCNP or other neurological or neuro-ophthalmic diseases * No strabismus * Have normal or near-normal vision with glasses or contact lenses. * Be able to provide informed consent and will be able to fluently read and understand spoken English Normal Group Exclusion Criteria: * Visual acuity worse than 20/100 in either eye * Greater than 4-line difference in visual acuity between the eyes * Structural anomalies or sensory sensitivities (e.g. visual motion sensitivity) that would prevent them from wearing or tolerating a VR headset * Known inability to tolerate visual testing of at least 20 minutes continuously.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Brooks Rehabilitation Hospital
RECRUITINGJacksonville, Florida, 32216, United States
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Vision Source of Worcester
RECRUITINGWorcester, Massachusetts, 01610, United States
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