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Computer-Guided surgery may sharpen tumor removal for jaw cancer patients

NCT ID NCT07306962

Knowledge-focused Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a computer-assisted method called virtual lesion segmentation can help surgeons remove mandibular ameloblastoma more precisely. Ten patients with this rare jaw tumor will have their surgery planned using 3D imaging to set a 10-mm safety margin. The goal is to see if this technique leads to negative margins and fewer recurrences.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Virtual lesion segmentation device
What this could lead to
If successful, this approach could help surgeons more accurately remove ameloblastoma tumors, potentially lowering the chance of the tumor coming back.
What could go wrong
This is a very small, early study with only 10 participants, so results may not apply to everyone. The technique is still experimental and needs more testing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients with histologically confirmed ameloblastoma using a preoperative biopsy. 2. Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle. Exclusion Criteria 1. Patients with lateral segmental mandibular defect involving the condyle. 2. Patients with an active infection at the site of resection. 3. Patients with recurrent lesion after resection.

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Conditions

The condition(s) this trial relates to.

ameloblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ameloblastoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, Alexandria University

    RECRUITING

    Alexandria, Alexandria Governorate, 21523, Egypt