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Leftover tumor tissue used to grow Mini-Tumors in lab

NCT ID NCT05786144

Knowledge-focused Sponsor: Maastricht Radiation Oncology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study took leftover tumor tissue from 100 patients undergoing surgery for vestibular schwannoma (a non-cancerous brain tumor) and used it to grow stem cell organoids—tiny 3D versions of the tumor—in the lab. The goal was to create a living biobank to study why these tumors resist treatment. No new treatments were tested; the focus was on understanding the tumor's biology.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Jun 2020

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with a supsicion for vestibular schwannoma on an MRI for which surgery was indicated (approximately 10 per year in Maastricht).

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * MRI with suspicion for vestibular schwannoma * Indication for surgery in the skull base committee * 18 years or older Exclusion Criteria: * Refusal to participate * Younger than 18 years * Incapacitated

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Conditions

The condition(s) this trial relates to.

acoustic neuroma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Vestibular schwannoma

Contacts and locations

Locations

  • Maastricht University Medical Center

    Maastricht, Limburg, 6229HX, Netherlands

  • Maastro

    Maastricht, Limburg, 6229ET, Netherlands

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