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Lung machine may also impact kidneys, study suggests

NCT ID NCT07368868

Knowledge-focused Sponsor: University Hospital, Ghent Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 76 ICU patients with severe pneumonia who were placed on a lung machine (ECMO) and given minimal ventilator support. Researchers wanted to see if this approach changed how well the kidneys worked. They reviewed medical records from 2019 to 2023, comparing urine output before and after starting ECMO. The goal is to learn more about how to protect kidneys during severe lung failure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand how to better protect kidneys in patients on ECMO for severe lung failure.
What could go wrong
This is a small, single-center retrospective study, so results may not apply to all patients. It only looks at past data, so it cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

76 people

The number who actually took part.

Started

Dec 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients admitted on the ICU of Ghent Univesity Hospital with acute respiratory distress who received support by veno-venous ECMO between 1 January 2019 and 31 December 2023

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Admission to the Intensive Care Unit (ICU) of Ghent University Hospital * Treatment with veno-venous extracorporeal membrane oxygenation (VV- ECMO) * ICU admission between 1 January 2019 and 31 December 2023 Exclusion Criteria: * Receipt of renal replacement therapy (RRT) prior to ICU admission * Patients already receiving VV-ECMO at the time of admission to the ICU of Ghent University Hospital (i.e., patients referred from another hospital on VV-ECMO) * Patients who received VV-ECMO immediately upon admission to the ICU of Ghent University Hospital

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Conditions

The condition(s) this trial relates to.

acute kidney injury acute lung injury acute respiratory distress syndrome pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury ARDS (acute respiratory distress syndrome) ECMO

Contacts and locations

Locations

  • Ghent university hospital

    Ghent, 9000, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.