Study reveals which IV fluids actually boost heart output
NCT ID NCT07499388
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how giving fluids through an IV affects blood flow in critically ill patients in the intensive care unit. Researchers want to see if only some of the fluid helps increase the heart's pumping ability. About 45 adults will be observed while they receive a standard fluid infusion.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Critically ill patients
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Critically ill patients admitted to the intensive care unit * Invasive or minimally invasive hemodynamic monitoring * Clinical indication for volume expansion with 500 mL of crystalloids Exclusion Criteria: * Suspected or confirmed pregnancy * Clinical conditions that may reduce the reliability of hemodynamic monitoring: * Severe aortic stenosis or regurgitation * Severe mitral stenosis or regurgitation * History of peripheral arterial disease * Clinical contraindications to the supine position
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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AOU delle Marche
RECRUITINGAncona, 60123, Italy
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