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New hope for tough leukemia cases: drug combo trial opens for kids and young adults

NCT ID NCT03826992

First seen Feb 20, 2026 · Last updated Jun 19, 2026 · Updated 14 times

Summary

This study is for children, teens, and young adults (ages 1 to 39) with acute leukemia that has come back or not gotten better with standard treatments. Researchers are testing whether combining two drugs—venetoclax and Vyxeos—is safe and tolerable. The goal is to find the best dose and see how well the combination works against the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

acute leukemia of ambiguous lineage acute myeloid leukemia acute undifferentiated leukemia B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) early T cell progenitor acute lymphoblastic leukemia leukemia mixed phenotype acute leukemia, B/myeloid mixed phenotype acute leukemia,T/myeloid myeloid sarcoma Recurrence T-cell acute lymphoblastic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.