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New drug combo targets hidden leukemia cells in early trial

NCT ID NCT06284486

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This study tests whether two drugs, venetoclax and revumenib, can control minimal residual disease (MRD) in acute myeloid leukemia (AML) patients. MRD means small numbers of cancer cells remain after initial treatment, raising the risk of relapse. The trial enrolls about 8 people aged 12 and older with specific genetic types of AML. The goal is to see if the combination is safe and can reduce or eliminate these leftover cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Email: •••••@•••••

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21218, United States

    Contact Email: •••••@•••••

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.