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Venetoclax under the microscope: Real-World CLL safety data released

NCT ID NCT04178317

Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how safe and effective Venetoclax is for people with chronic lymphocytic leukemia (CLL) when used in everyday medical practice. Fourteen patients were followed to track side effects and how well the drug worked. The goal was to monitor real-world use, not to test a new cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

14 people

The number who actually took part.

Started

Apr 2020

Finished

Aug 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

\- Participants with chronic lymphocytic leukemia (CLL) who are prescribed venetoclax within the approved label according to physician judgement.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants diagnosed with chronic lymphocytic leukemia who have been prescribed Venetoclax for the first time according to the approved label * Participants (and/or legal representative) who voluntarily agree to participate in this study and sign informed consent Exclusion Criteria: -Participants with contraindications to venetoclax as listed on the approved local label

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer, chronic lymphocytic leukemia (CLL)

Contacts and locations

Locations

  • Ajou University Hospital /ID# 249512

    Suwon, Gyeonggido, 16499, South Korea

  • Chonnam National University Hwasun Hospital /ID# 216849

    Hwasun-gun, Jeonranamdo, 58128, South Korea

  • Inje University - Busan Paik Hospital /ID# 233882

    Busan, Busan Gwang Yeogsi, 47392, South Korea

  • Korea University Anam Hospital /ID# 216851

    Seoul, Seoul Teugbyeolsi, 02841, South Korea

  • Kyungpook National University Hospital /ID# 233884

    Daegu, Daegu Gwang Yeogsi, 41944, South Korea

  • Pusan National University Hospital /ID# 216850

    Busan, Busan Gwang Yeogsi, 49241, South Korea

  • Samsung Medical Center /ID# 217180

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Seoul National University Hospital /ID# 216853

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • The Catholic University of Korea, Seoul St. Marys Hospital /ID# 216852

    Seoul, Seoul Teugbyeolsi, 06591, South Korea

  • The Catholic University of Korea, Seoul St. Marys Hospital /ID# 217181

    Seoul, Seoul Teugbyeolsi, 06591, South Korea

  • The Catholic University of Korea, Yeouido ST. Mary's Hospital /ID# 217179

    Seoul, Seoul Teugbyeolsi, 07345, South Korea

  • The catholic university of korea st. Paul's hospital /ID# 238907

    Seoul, Gyeonggido, 03300, South Korea

  • Yonsei University Health System Severance Hospital /ID# 215348

    Seoul, 03722, South Korea