New combo aims to wipe out stubborn leukemia cells
NCT ID NCT03128879
First seen Nov 21, 2025 · Last updated Jun 16, 2026 · Updated 24 times
Summary
This study tests whether adding venetoclax to ongoing ibrutinib or acalabrutinib treatment can eliminate remaining leukemia cells in people with high-risk chronic lymphocytic leukemia (CLL). Participants must have been on their current therapy for at least 12 months and still have detectable disease. The goal is to achieve undetectable minimal residual disease (MRD) in the bone marrow, which means no cancer cells can be found with sensitive testing.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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The condition terms exactly as the trial's registrant entered them.