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Two-Drug combo shows promise against Hard-to-Treat leukemia

NCT ID NCT02756897

First seen Mar 05, 2026 · Last updated May 25, 2026 · Updated 8 times

Summary

This study tested a combination of two targeted drugs, venetoclax and ibrutinib, in 234 people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma. The goal was to see how well the drugs control the cancer, especially in patients whose disease came back or had high-risk features. Participants took both pills daily, and researchers tracked tumor shrinkage and side effects like low blood counts or infections.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.