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Triple-Drug attack shows promise for Hard-to-Treat cancers

NCT ID NCT01787500

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 33 times

Summary

This early-stage trial tested a combination of three drugs—vemurafenib, cetuximab, and irinotecan—in 47 people with advanced solid tumors that have a specific BRAF V600 mutation and cannot be removed by surgery. The main goal was to find the safest dose and understand side effects. The approach aims to block cancer growth and help the immune system fight the tumor, but ongoing treatment is needed to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.