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New study tests which vancomycin dosing method is safer for kidneys

NCT ID NCT05823116

First seen Jan 05, 2026 · Last updated Jun 21, 2026 · Updated 24 times

Summary

This study looked at how giving the antibiotic vancomycin continuously versus intermittently affects kidney function and injury markers. Thirty-seven hospitalized adults were randomly assigned to one of the two infusion methods. Researchers measured changes in kidney filtration rate and specific injury biomarkers to see if one method is gentler on the kidneys.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Kentucky

    Lexington, Kentucky, 40506, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vancomycin

What this could lead to

If successful, this study could help doctors choose the safest way to give vancomycin to reduce kidney damage in hospitalized patients.

What could go wrong

This is a small, completed Phase 4 trial with only 37 participants, so results may not apply to all patients. The study measures biomarkers, not long-term health outcomes.

Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.