Can a leg cross or a blink reveal hidden consciousness?
NCT ID NCT07786298
First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time
Summary
This study aims to validate new behavioral indicators of consciousness in healthy, fully conscious adults. Researchers will check whether signs like leg crossing, responses to touch, or blink rate are reliably present in conscious individuals. If confirmed, these signs could help improve the assessment of patients with disorders of consciousness, such as those in a coma or vegetative state. The study involves 100 French-speaking adults with no neurological or psychiatric conditions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Behavioral assessment using the Additional Signs of Consciousness (ASC) Scale
- What this could lead to
- If these behavioral signs are confirmed in healthy people, they could become reliable tools to better detect consciousness in patients with disorders of consciousness, improving diagnosis and care decisions.
- What could go wrong
- This is an early validation study in healthy volunteers, not patients. The signs may not translate to real-world clinical use, and the study does not test treatments or outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Volunteer participants without disorders of consciousness
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult, French-speaking individuals with no neurological and/or psychiatric disorders or history thereof, and no uncorrected sensorimotor deficits. Exclusion Criteria: * Minors, non-French-speaking individuals, individuals with neurological and/or psychiatric disorders or a history thereof, and individuals with uncorrected sensorimotor deficits.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Coma Science Group
Liège, 4000, Belgium