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Ear zaps aim to tame stomach troubles

NCT ID NCT06491758

First seen Mar 10, 2026

Summary

This study tests whether electrically stimulating a nerve in the ear can reach the internal vagus nerve, which controls stomach function. Researchers will measure nerve signals and stomach activity in 131 healthy volunteers and people with gastroparesis. The goal is to see if this ear stimulation method could one day treat nausea, vomiting, and other stomach issues.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Indiana University

    Indianapolis, Indiana, 46202, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

electrical stimulation of the ear

What this could lead to

If successful, this could lead to a non-invasive way to treat nausea, vomiting, and stomach disorders by stimulating the vagus nerve through the ear.

What could go wrong

This is an early-phase study focused on measuring nerve signals, not on treatment outcomes. It may not lead to a practical therapy, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

gastroparesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.