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Dialysis patients may get better vaccine protection with a common transplant drug

NCT ID NCT07587801

First seen May 18, 2026 · Last updated Jun 23, 2026 · Updated 4 times

Summary

This study tests whether taking a short course of the drug sirolimus (Rapamycin) can improve how well older adults on hemodialysis respond to flu and RSV vaccines. Sixty participants will receive the vaccines plus sirolimus at different times. The goal is to see if this approach strengthens immune memory against these viruses.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sirolimus (Rapamycin)

What this could lead to

If it works, this could point toward a way to improve vaccine protection for people with weakened immune systems, like those on dialysis.

What could go wrong

This is a small, early-phase trial (60 people) and the drug may not improve vaccine response or could cause side effects. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

end stage renal failure influenza

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.