Texts and letters aim to boost HPV shots in rural teens
NCT ID NCT05148559
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether sending vaccine reminders by text, email, or mail can increase HPV vaccination rates among 12-year-olds in rural areas, where uptake is lower. Over 5,400 teens in a regional healthcare system are enrolled. Parents receive reminders every other month until their child is fully vaccinated or turns 13.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- vaccine reminder notices (text, email, or mailed letter)
- What this could lead to
- If it works, this could show a simple way to increase vaccination rates in rural areas, helping prevent HPV-related cancers.
- What could go wrong
- This is a behavioral study, not a drug trial. Results may vary by region and may not apply to all communities. Reminders alone may not overcome other barriers like access or hesitancy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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5,451 people
The number who actually took part.
- Started
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Aug 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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12 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Marshfield Clinic Health System patient aged 12 years with at least one preventive visit or two evaluation \& management visits with a Marshfield Clinic Health System provider in the last 36 months * Due for at least one adolescent vaccine (HPV, MenACWY, Tdap) Exclusion Criteria: * Primary care provider is not affiliated with Marshfield Clinic Health System * Opted out of Marshfield Clinic Health System vaccine reminder notifications * Missing or invalid contact information * Deceased
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Marshfield Clinic Health System
Marshfield, Wisconsin, 54449, United States
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