MRI scans reveal why some Women's menstrual pain resists naproxen
NCT ID NCT04145518
First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 20 times
Summary
This completed study used MRI scans to understand why menstrual pain happens and how the drug naproxen relieves it. Researchers studied 183 women with and without conditions like endometriosis or fibroids. They aimed to identify different pain types based on uterine activity, blood flow, and oxygen levels, and to see why naproxen works for some but not others.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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NorthShore University HealthSystem
Evanston, Illinois, 60201, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Naproxen Sodium
What this could lead to
If successful, this study could lead to better ways to diagnose and treat menstrual pain by identifying different pain types and why some people don't respond to naproxen.
What could go wrong
This is a small, completed study focused on understanding pain mechanisms, not testing a new treatment. The findings may not directly change clinical practice or benefit patients immediately.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.