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New shot targets tough blood cancers in early trial
NCT ID NCT07338604
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new injection called UTAA07 for adults with CD7-positive blood cancers that have come back or not responded to treatment. The main goals are to check safety and find the best dose. Only 15 people will take part in this early-stage trial.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged ≥ 18 years, regardless of gender. * Expected survival time ≥ 3 months. * ECOG performance status score of 0-1. * Confirmed diagnosis of relapsed/refractory CD7-positive hematolymphoid malignancies at screening. * Coagulation function, liver and kidney function, and cardiopulmonary function meeting the requirements. * Ability to understand the trial and signed informed consent form. Exclusion Criteria: * A history of malignant tumors other than hematolymphoid malignancies within 5 years prior to screening, excluding carcinoma in situ. * Positive results for virological tests or syphilis. * Severe cardiac diseases. * Unstable systemic diseases as determined by the investigator. * Active or uncontrolled infections requiring systemic treatment within 7 days prior to screening, excluding mild urinary and reproductive system infections and upper respiratory tract infections. * Pregnant or lactating women; female subjects planning to become pregnant within 2 years after cell infusion; or male subjects whose partners plan to become pregnant within 2 years after the subject's cell infusion. * Subjects receiving systemic corticosteroid therapy within 7 days prior to screening, or those judged by the investigator to require long-term systemic corticosteroid therapy during the trial period, excluding inhaled or topical administration. * Participation in other clinical studies within 1 month prior to screening. * Evidence of central nervous system (CNS) involvement at screening, such as detection of tumor cells in cerebrospinal fluid (CSF) or imaging findings suggestive of CNS infiltration. * Patients requiring long-term use of immunosuppressants as determined by the investigator at screening. * A history of epilepsy or other central nervous system diseases. * Patients with primary immunodeficiency diseases. * Other circumstances deemed inappropriate for enrollment by the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital of Soochow University
RECRUITINGSuzhou, Jiangsu, 215000, China
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