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Potassium citrate may offer antibiotic-free UTI relief

NCT ID NCT07202832

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether potassium citrate, a medication that makes urine less acidic, can relieve painful UTI symptoms in women aged 18-50. Fifty participants will take either potassium citrate or the antibiotic nitrofurantoin for 7 days. Researchers will compare symptom scores and urine culture results to see if the alkalinizer works as well as the antibiotic.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
potassium citrate
What this could lead to
If it works, this could offer a non-antibiotic option for relieving UTI symptoms, potentially reducing antibiotic use.
What could go wrong
This is a small, early-stage trial with only 50 participants. It may not show clear benefit, and potassium citrate might not clear the infection as well as antibiotics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2025

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged ≥ 18 and ≤ 50. * Symptoms of uncomplicated UTI or cystitis; including urinary frequency, urgency and dysuria. * Positive urine culture of mid-urine urine. Exclusion Criteria: * Post menopausal women. * Pregnancy. * Complicated UTIs, such as those requiring hospital admission, infections associated with fevers, those with urinary tract abnormalities, urinary tract calculi or urinary tract obstruction. * History of recurrent UTI. * Recent antibiotic use. * Acute pyelonephritis. * Immunocompromising conditions. * Chronic conditions such as interstitial cystitis, painful bladder syndrome, chronic pelvic pain syndrome. * Patients with CKD. * Patients with allergy to potassium citrate.

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Conditions

The condition(s) this trial relates to.

urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

UTI - urinary tract infection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Urology Department, Faculty of Medicine, Assiut University

    Asyut, Asyut Governorate, 71515, Egypt

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