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New eczema drug shows promise in long-term real-world study

NCT ID NCT05139836

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study follows about 772 teenagers and adults with moderate to severe eczema who are taking upadacitinib (Rinvoq) as prescribed by their doctor. Researchers want to see how well the drug controls the disease over two years in everyday medical practice. Participants will have regular check-ups, fill out questionnaires, and be monitored for side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

634 people

The number who actually took part.

Started

Dec 2021

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adolescent and adult participants with atopic dermatitis who have been prescribed upadacitinib in the course of routine practice according to relevant approved licenses.

Ages

12 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Body weight \>=30 kg at baseline for participants between \>=12 and \<18 years of age. * Physician confirmed diagnosis of moderate to severe atopic dermatitis at the time of enrollment. * Upadacitinib initiated as per the local label. The decision to prescribe upadacitinib must have been made prior to and independently of study participation. * Medical and medication history available at least for the last 6 months. Exclusion Criteria: \- Current participation in interventional research (note: this does not include non-interventional, post-marketing observational studies, or registry participation).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Albrecht, Wurzen, DE /ID# 241988

    Wurzen, 04808, Germany

  • Barnikol, Waltershausen, DE /ID# 241844

    Waltershausen, 99880, Germany

  • Barth, Borna, DE /ID# 248871

    Borna, 04552, Germany

  • Beldio Research GmbH /ID# 245830

    Memmingen, Bavaria, 87700, Germany

  • Bell, Andernach, DE /ID# 249154

    Andernach, Rhineland-Palatinate, 56626, Germany

  • Brinkmann & Partner, Gladbeck, /ID# 241850

    Gladbeck, 45964, Germany

  • CMS3 Company for Medical Study /ID# 241659

    Selters, Rhineland-Palatinate, 56242, Germany

  • Cutaneum /ID# 249104

    Hamburg, 20249, Germany

  • Derma Köln /ID# 241856

    Cologne, 50737, Germany

  • Derma Sana /ID# 241854

    Karlsruhe, 76133, Germany

  • Dermatologie Kleinmachnow /ID# 268383

    Kleinmachnow, Brandenburg, 14532, Germany

  • Dermatologie Moelln Praxis Dr. Bodo Segert /ID# 242280

    Mölln, Schleswig-Holstein, 23879, Germany

  • Dermatologie Quist-BAG Dres. med. Quist PartG /ID# 243325

    Mainz, 55128, Germany

  • Dermatologie im Apfelgarten /ID# 263704

    Neu Wulmstorf, 21629, Germany

  • Dermatologie im Tal Praxis Dr.med. Maria Leibl /ID# 266128

    Munich, 80331, Germany

  • Dermatologikum Hamburg /ID# 245431

    Hamburg, 20354, Germany

  • Dermatologische Praxis Kempen /ID# 248852

    Kempen, 47906, Germany

  • Dermatologisches Studienzentrum am Haut- und Laserzentrum /ID# 243882

    Simmern, Rhineland-Palatinate, 55469, Germany

  • Dermazent /Id# 268146

    Munich, Bavaria, 80331, Germany

  • Dr. Barbara Kempkes, Werne /ID# 241910

    Werne, 59368, Germany

  • Dr. Buerkle /ID# 250299

    Haslach im Kinzigtal, 77716, Germany

  • Dr. Gißler-Walter /ID# 248876

    Mutterstadt, 67112, Germany

  • Dr. Hoffmann /ID# 245423

    Cologne, 50674, Germany

  • Dr. Krueger /ID# 265150

    Goslar, 38640, Germany

  • Dr. Rezai /ID# 250298

    Münster, 48143, Germany

  • Dr. Schaefers /ID# 255492

    Reutlingen, 72764, Germany

  • Dr. Stoeber /ID# 251066

    Ahlen, 59227, Germany

  • Dr. Wrage-Brors /ID# 262705

    Hamburg, 22179, Germany

  • Dr. med. Nicola Moller and Thomas Kurtenbach GbR Dermatologie im Zentrum /ID# 266130

    Wiesbaden, Hesse, 65185, Germany

  • Dres. Jacobs & Kollegen /ID# 241989

    Kulmbach, 95326, Germany

  • Dues/Manasterski, Berlin, DE /ID# 243885

    Berlin, 13507, Germany

  • Duplicate_Hautarztpraxis Luetten/Sack /ID# 241534

    Hamburg, 21109, Germany

  • Durani & Durani, Heidelberg,DE /ID# 249172

    Heidelberg, Baden-Wurttemberg, 69115, Germany

  • Flegl MD Stuttgart Germany /ID# 250302

    Stuttgart, Baden-Wurttemberg, 70567, Germany

  • Gemeinschaftspraxis Dres. Anika Hünermund/Mario Pawlak /ID# 241908

    Heilbad Heiligenstadt, 37308, Germany

  • Gemeinschaftspraxis Rietkoetter und Jablonka /ID# 241821

    Gelsenkirchen, 45899, Germany

  • Gemeinschaftspraxis fur Dermatologie /ID# 245831

    Stadtroda, 07646, Germany

  • Grossmann, Grossenhain, DE /ID# 250303

    Großenhain, 01558, Germany

  • Grossmann, Koblenz, DE /ID# 242992

    Koblenz, Rhineland-Palatinate, 56068, Germany

  • HMS GmbH Zimmer /ID# 241657

    Merzig, Saarland, 66663, Germany

  • Hagemeier, Loehne, DE /ID# 241886

    Löhne, 32584, Germany

  • Harzklinikum Dorothea Christiane Erxleben /ID# 251067

    Quedlinburg, 06484, Germany

  • Hausarztpraxis & Laserzentrum Dr. Zimmermann & Kollegen /ID# 251051

    Heusenstamm, 63150, Germany

  • Hausärzte am Fastnachtsbrunnen /ID# 250304

    Mainz, 55116, Germany

  • Haut Pur - Dermatologische Gemeinschaftspraxis /ID# 243943

    Berlin, 13597, Germany

  • Haut- u. Laserzentrum Heilbronn /ID# 250305

    Heilbronn, 74072, Germany

  • Haut- und Allergie-Zentrum Lippstadt /ID# 241929

    Lippstadt, 59557, Germany

  • Hautarzte im Novum Medicum Dr. Kreienkamp & Sautter /ID# 276060

    Würzburg, Bavaria, 97080, Germany

  • Hautarztpraxis Dr. Alexander Magerl /ID# 270749

    Bensheim, Hesse, 64625, Germany

  • Hautarztpraxis Dr. Budihardja /ID# 241851

    Giessen, 35392, Germany

  • Hautarztpraxis Dr. Kirschner /ID# 266738

    Mainz, Rhineland-Palatinate, 55116, Germany

  • Hautarztpraxis Dr. Weid /ID# 265213

    Bingen am Rhein, 55411, Germany

  • Hautarztpraxis Dr. med. Christiane Handrick /ID# 262667

    Berlin, 10117, Germany

  • Hautarztpraxis Dr. med. Matthias Hoffmann /ID# 241907

    Witten, 58453, Germany

  • Hautarztpraxis Friedberg Dr. med. Wilfried Jungkunz /ID# 248851

    Friedberg (Hessen), 61169, Germany

  • Hautarztpraxis Haßberge /ID# 257648

    Haßfurt, 97437, Germany

  • Hautarztpraxis Langenau /ID# 242279

    Langenau, Baden-Wurttemberg, 89129, Germany

  • Hautarztpraxis Weidgang /ID# 248850

    Jülich, 52428, Germany

  • Hautarztzentrum Tegel /ID# 241826

    Berlin, 13507, Germany

  • Hautcentrum Wiesbaden /ID# 274848

    Wiesbaden, Hesse, 65183, Germany

  • Hautmedizin Delitzsch /ID# 251394

    Delitzsch, 04509, Germany

  • Hautzentrum am Marienplatz /ID# 248847

    Munich, 80331, Germany

  • Hautärzte am Nauener Tor /ID# 261533

    Potsdam, Brandenburg, 14469, Germany

  • Herrmann, Greifswald, DE /ID# 241889

    Greifswald, Mecklenburg-Vorpommern, 17489, Germany

  • Hockmann, Oelde, DE /ID# 241906

    Oelde, 59302, Germany

  • Hoeller-Obrigkeit, Aachen, DE /ID# 245430

    Aachen, North Rhine-Westphalia, 52064, Germany

  • Jasnoch/Kock/Borrosch, Vechta, /ID# 252081

    Vechta, 49377, Germany

  • Karl, Soest, DE /ID# 241909

    Soest, North Rhine-Westphalia, 59494, Germany

  • Katholisches Klinikum Bochum gGmbH /ID# 270537

    Bochum, North Rhine-Westphalia, 44791, Germany

  • Klinikum Rosenhoehe /ID# 241601

    Bielefeld, North Rhine-Westphalia, 33647, Germany

  • Kors, Berlin, DE /ID# 241847

    Berlin, 13086, Germany

  • Kramer/Mortazawi, Remscheid /ID# 241824

    Remscheid, North Rhine-Westphalia, 42897, Germany

  • Kurzen, Freising, DE /ID# 241845

    Freising, Bavaria, 85354, Germany

  • Loth, Gernsbach, DE /ID# 241828

    Gernsbach, 76593, Germany

  • MVZ "Im Altstadtquartier" Magdeburg /ID# 261366

    Magdeburg, 39104, Germany

  • MVZ Prof. Dr. Ockenfels Haut- und Allergie-Praxisklinik GmbH /ID# 245395

    Hanau, 63450, Germany

  • MVZ medicum.mittelhessen /ID# 266126

    Bad Camberg, 65520, Germany

  • Magdeburger Company for Medical Studies & Services GmbH /ID# 248849

    Magdeburg, 39104, Germany

  • Mauer, Bad Kreuznach, DE /ID# 241990

    Bad Kreuznach, 55543, Germany

  • MediCorium Zentrum fuer Dermatologie und Aesthetik /ID# 243328

    Oberursel, Hesse, 61440, Germany

  • MediCorium Zentrum fuer Dermatologie und Aesthetik /ID# 249180

    Oberursel, Hesse, 61440, Germany

  • Mensing Derma MVZ GmbH /ID# 272383

    Hamburg, 22391, Germany

  • Neubauer, Leipzig, DE /ID# 241823

    Leipzig, Saxony, 04209, Germany

  • Petri, Ahaus, DE /ID# 243452

    Ahaus, 48683, Germany

  • Praxis A. Viculova /ID# 266133

    Miltenberg, 63897, Germany

  • Praxis Dehmel / Brand-Opitzer /ID# 243884

    Wasserburg A. Inn, 83512, Germany

  • Praxis Dermatologie am Savigny /ID# 248846

    Berlin, 10623, Germany

  • Praxis Dr. Asadullah /ID# 243944

    Potsdam, Brandenburg, 14467, Germany

  • Praxis Dr. Behnke /ID# 248870

    Panketal, Brandenburg, 16341, Germany

  • Praxis Dr. Fränken /ID# 241853

    Schwelm, 58332, Germany

  • Praxis Dr. Konstantin Ertner /ID# 249153

    Nuremberg, 90402, Germany

  • Praxis Dr. Korge /ID# 241531

    Düren, 52349, Germany

  • Praxis Dr. Lange /ID# 241829

    Gera, 07548, Germany

  • Praxis Dr. Mempel /ID# 241827

    Elmshorn, Schleswig-Holstein, 25335, Germany

  • Praxis Dr. Mihaescu /ID# 241825

    Augsburg, 86150, Germany

  • Praxis Dr. Raschke /ID# 251398

    Magdeburg, Saxony-Anhalt, 39104, Germany

  • Praxis Dr. Sbornik /ID# 241818

    Deggendorf, 94469, Germany

  • Praxis Dr. Termeer /ID# 241662

    Stuttgart, 70499, Germany

  • Praxis Dr. Wegener /ID# 263731

    Hamburg, 20095, Germany

  • Praxis Dres. Bischoff/Danz /ID# 241852

    Ilmenau, 98693, Germany

  • Praxis Dres. Bornemann/Reinerth /ID# 257649

    Krefeld, 47798, Germany

  • Praxis Dres. Freitag/Knoell /ID# 242278

    Falkensee, Brandenburg, 14612, Germany

  • Praxis Dres. Kaspari /Schenck /ID# 241688

    Hanover, Lower Saxony, 30159, Germany

  • Praxis Dres. Wiemers/Wiemers /ID# 241602

    Leipzig, 04317, Germany

  • Praxis Liebetrau /ID# 271896

    Friedrichroda, Thuringia, 99894, Germany

  • Praxis P. Hausler-Mehlhorn /ID# 241527

    Chemnitz, Saxony, 09130, Germany

  • Praxis T. Schadeck /ID# 241768

    Bogen, 94327, Germany

  • Praxis fuer Innere Medizin/Rheumatologie /ID# 241846

    Blaubeuren Abbey, 89143, Germany

  • Private Practice - Dr. Daniela Kasche - Langelohstrasse /ID# 249102

    Hamburg, 22549, Germany

  • Private Practice - Dr. Gellrich, Dr. Klein and Dr. Soost /ID# 250301

    Berlin, 12247, Germany

  • Private Practice - Dr. Sung-Hei Hong-Weldemann /ID# 248844

    Freiburg im Breisgau, Baden-Wurttemberg, 79098, Germany

  • Quack, Munich, DE /ID# 241536

    Munich, 81539, Germany

  • Richter-Huhn, Dresden, DE /ID# 241822

    Dresden, 01219, Germany

  • Rotterdam, Gelsenkirchen, DE /ID# 241819

    Gelsenkirchen, 45897, Germany

  • Schirmer, Berlin, DE /ID# 241684

    Berlin, 12489, Germany

  • Schwichtenberg, Bremen, DE /ID# 241683

    Bremen, 28779, Germany

  • Stockmeier, Ingoldstadt, DE /ID# 248877

    Ingolstadt, 85049, Germany

  • Studienzentrum an der Hase GbR Dr. Weyergraf/Dr. Frick/Thomas Heiber /ID# 241658

    Bramsche, Lower Saxony, 49565, Germany

  • Timmel/Timm/Vorwerk, Bergen /ID# 241661

    Bergen, 18528, Germany

  • Universitaetsklinik Heidelberg /ID# 245834

    Heidelberg, Baden-Wurttemberg, 69120, Germany

  • Universitaetsklinikum Frankfurt /ID# 241766

    Frankfurt am Main, Hesse, 60590, Germany

  • Universitaetsklinikum Magdeburg /ID# 249174

    Magdeburg, 39120, Germany

  • Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 240096

    Kiel, Schleswig-Holstein, 24105, Germany

  • Voelkel, Nuremberg, DE /ID# 252445

    Nuremberg, Bavaria, 90419, Germany

  • ZENTderma /ID# 241539

    Mönchengladbach, 41061, Germany

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