Underwater colon surgery may be easier and safer
NCT ID NCT07490574
First seen Apr 15, 2026 · Last updated Jun 23, 2026 · Updated 12 times
Summary
This study tested a new method called underwater endoscopic submucosal dissection (UESD) for removing large, non-cancerous colon growths. In UESD, the colon is filled with saline instead of gas, which may improve visibility and make the procedure faster. The trial involved 295 adults across multiple Italian centers and compared UESD to the standard gas-assisted technique. The main goal was to see if UESD could remove the entire growth in one piece just as well as the standard method.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Campus Bio Medico Hospital
Rome, RM, 00100, Italy
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Underwater endoscopic submucosal dissection (UESD) procedure
What this could lead to
If successful, this could make removing large colorectal growths easier, faster, and safer for patients.
What could go wrong
This is a completed trial comparing two procedures, so results are known. The benefit may be small and not change standard practice significantly.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.