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Ultrasound to reveal if cosmetic creams can melt away foot calluses and corns

NCT ID NCT07765225

Symptom relief Sponsor: Wroclaw University of Health and Sport Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This study tests whether a cosmetic serum and cream containing urea, salicylic acid, and collagen can reduce the thickness and pain of foot calluses and corns. Adult women with a single callus or corn will apply the treatment twice daily for two months. High-frequency ultrasound is used to precisely measure changes in lesion thickness before and after treatment, comparing treated and untreated groups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A topical cosmetic serum and cream containing urea, salicylic acid, and collagen, applied twice daily for two months.
What this could lead to
If effective, this cosmetic treatment could offer a non-invasive way to reduce the thickness and pain of foot calluses and corns, potentially improving comfort and foot health.
What could go wrong
This is a small, non-randomized study, so results may not be conclusive. The treatment is cosmetic, not medicinal, and may not work for everyone. There is a risk of skin irritation from the active ingredients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

124 people

The number who actually took part.

Started

Feb 2020

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult women aged 35-65 years. * Presence of a single non-infectious hyperkeratotic foot lesion classified as either a callus or a corn. * Written informed consent provided prior to study initiation. Exclusion Criteria: * Known allergy or hypersensitivity to salicylic acid, salicylates, or other formulation ingredients. * Active dermatological conditions, skin diseases, or epidermal fissures on the lower extremities. * Diabetes mellitus. * Active cardiovascular disorders or local inflammatory conditions.

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Conditions

The condition(s) this trial relates to.

Callosities Foot Dermatoses Keratoderma, Palmoplantar, Epidermolytic keratosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Callus Corn (clavus) Foot dermatoses Hyperkeratosis

Contacts and locations

Locations

  • OSTEON Clinic

    Swidnica, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.