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Could a simple back injection replace morphine after kidney stone surgery?

NCT ID NCT07672600

Symptom relief Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 29, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study tests whether an ultrasound-guided nerve block (erector spinae plane block) can reduce pain and the need for morphine after percutaneous nephrolithotomy, a surgery to remove large kidney stones. Fifty-six adults undergoing elective surgery will be randomly assigned to receive either the nerve block or standard intravenous pain relief. The main goal is to measure total morphine use over 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Erector Spinae Plane Block (nerve block procedure)
What this could lead to
If effective, this nerve block could become a standard way to reduce pain and the need for strong painkillers after kidney stone surgery.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. The nerve block may not provide significant pain relief and carries rare risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Oct 2019

Finished

Apr 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elective percutaneous nephrolitotomy * American Society of Anesthesiologists (ASA) physical status I-II Exclusion Criteria: * Refusal to participate * Coagulopathy, * Infection at the block site * Allergy to local anaesthetics * Previous surgery in the block area * Severe systemic disease.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute postoperative pain in urological surgery Regional anaesthesia

Contacts and locations

Locations

  • Istanbul University, Istanbul Faculty of Medicine

    Istanbul, Fatih, 34093, Turkey (Türkiye)

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