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Ultrasound could reveal hidden muscle activity in spinal stimulation

NCT ID NCT07206797

Knowledge-focused Sponsor: North Carolina State University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether ultrasound can measure muscle activation caused by two types of stimulation: non-invasive spinal cord stimulation and functional electrical stimulation. Researchers will apply these stimulations to the ankle muscles of 30 healthy adults and compare the resulting torque and ultrasound images. The goal is to see if ultrasound can reliably track muscle activity, which could help improve therapies for people with spinal cord injury.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could show that ultrasound is a useful tool to measure muscle activity during stimulation, potentially improving rehabilitation strategies for people with spinal cord injury.
What could go wrong
This is a small, early-stage study in healthy volunteers, not patients. The results may not directly apply to people with spinal cord injury, and the technique may not work as expected in real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Between 18 and 60 years of age * Weight less than 220 lb * Healthy and able to walk at preferred speed without an assistive device * Able to tolerate functional electrical stimulation and tSCS. Exclusion Criteria: * Active infection * history of cancer, * broken skin, sores, or areas of acute eczema near the electrode sites * metal implants, such as staples or pins, near the electrode sites * any neurological disorders * difficulty walking or an orthopedic condition that would impede walking normally without assistance * absent sensation in the lower extremities or trunk (torso), * allergies to adhesive skin tapes and/or ultrasound gels, * heart conditions * an implanted electronic device such as a pacemaker * current pregnancy * having no physiological response to FES and/or tSCS.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuromodulatory effects of TSCS and fes in lower limbs

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Engineering Building III

    RECRUITING

    Raleigh, North Carolina, 27695, United States

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