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Ultrasound test aims to speed up diagnosis of breathing emergencies

NCT ID NCT07324980

Diagnosis Sponsor: Università degli Studi del Piemonte Orientale Amedeo Avogadro Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a bedside ultrasound of a large vein (the inferior vena cava) can help emergency doctors quickly tell if a patient's breathing trouble is caused by fluid buildup in the lungs from heart failure or from another cause. Researchers will enroll 200 adults with sudden breathing problems and compare ultrasound results with standard tests. The goal is to improve early diagnosis and treatment decisions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Nov 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients presenting to the emergency department with acute dyspnea and acute respiratory failure, undergoing standard diagnostic evaluation and clinical management as part of routine care.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged ≥18 years. * Presentation to the emergency department with acute dyspnea and acute respiratory failure, defined by at least one of the following: * PaO₂ \< 60 mmHg on room air, or * Oxygen saturation (SpO₂) \< 90% on room air, or * PaO₂/FiO₂ ratio \< 300. * Ability to provide written informed consent or eligibility for deferred consent according to local regulations. * Undergoing standard diagnostic evaluation including laboratory tests and chest imaging as part of routine clinical care. Exclusion Criteria: * Refusal to provide informed consent (or consent by legal representative when applicable). * Inadequate ultrasound window or technically insufficient ultrasound assessment. * Acute respiratory failure secondary to chest trauma. * Cardiac arrest at presentation or during emergency department stabilization. * Requirement for invasive mechanical ventilation during initial stabilization in the emergency department.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure Dyspnea pulmonary edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute respiratory failure Dyspnea Hydrostatic pulmonary edema

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Azienda Ospedaliero-Universitaria Maggiore della Carità

    RECRUITING

    Novara, 28100, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.