New drugs aim to slow type 1 diabetes in its tracks

NCT ID NCT05743244

Ongoing Disease control Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Source: ClinicalTrials.gov ↗

Summary

This study is testing two experimental drugs, abrocitinib and ritlecitinib, to see if they can help preserve the body's remaining insulin-producing cells in people recently diagnosed with type 1 diabetes. The trial involves 78 participants aged 12-35 who were diagnosed within the last 100 days. Participants will take one of the drugs or a placebo for 12 months, with researchers measuring their insulin production and overall health to see if the treatment helps.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

3. Royal Melbourne Hospital

Parkville, Victoria, 3050, Australia
Barbara Davis Center at University of Colorado Anschutz Medical Campus

Aurora, Colorado, 80045, United States
Benaroya Research Institute

Seattle, Washington, 98101, United States
Children's Hospital Orange County

Orange, California, 92868, United States
Columbia University-Naomi Berrie Diabetes Center

New York, New York, 10032, United States
Emory Children's Center

Atlanta, Georgia, 30322, United States
Hospital for Sick Children

Toronto, Ontario, M5G1X8, Canada
Indiana University

Indianapolis, Indiana, 46202, United States
Joslin Center at SUNY Upsate

Syracuse, New York, 13210, United States
Joslin Diabetes Center

Boston, Massachusetts, 02215, United States
Perth Children's Hospital

Nedlands, Western Australia, 6009, Australia
Queensland Children's Hospital

South Brisbane, Queensland, 4101, Australia
Royal North Shore Hospital

Saint Leonards, New South Wales, 2065, Australia
Stanford University

Palo Alto, California, 94304, United States
The Children's Mercy Hospital

Kansas City, Missouri, 64111, United States
The Royal Children's Hospital - Melbourne

Melbourne, Victoria, 3052, Australia
UBMD Pediatrics

Buffalo, New York, 14203, United States
University of California- San Francisco

San Francisco, California, 94143, United States
University of Chicago

Chicago, Illinois, 60637, United States
University of Florida

Gainesville, Florida, 32610, United States
University of Louisville Pediatric Endocrinology

Louisville, Kentucky, 40202, United States
University of Miami

Miami, Florida, 33136, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15224, United States
University of South Florida Diabetes Center

Tampa, Florida, 33612, United States
University of Texas Southwestern

Dallas, Texas, 75390, United States
University of Utah

Salt Lake City, Utah, 84112, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Women and Children's Hospital-Adelaide

Adelaide, South Australia, 5006, Australia
Yale University School of Medicine

New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.

DIABETES MELLITUS TYPE 1