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New study tests quick scoring tool for testicular torsion in adults

NCT ID NCT07499024

Diagnosis Sponsor: University Hospital, Linkoeping Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a simple scoring system called TWIST can accurately rule out testicular torsion in adult men with sudden scrotal pain. Researchers will enroll 1,000 men aged 18-40 at Swedish emergency departments. If the score works, it could reduce the need for unnecessary ultrasounds and speed up care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a reliable, quick way to rule out testicular torsion without needing an ultrasound, saving time and resources.
What could go wrong
This is an observational study, not a treatment trial. The tool was designed for children, so it may not work as well in adults. Results are still being collected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult men aged 18-40 years presenting to participating Emergency Departments in Sweden with acute scrotal pain or scrotal symptoms suggestive of testicular torsion. Patients with trauma-related scrotal pain, symptom duration longer than one week, previous testicular surgery, or inability to provide informed consent are excluded. The study aims to evaluate the diagnostic accuracy of the TWIST score in a real-world adult ED population.

Ages

18 to 40 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male patients aged 18-40 years Presenting to the Emergency Department with acute scrotal pain or scrotal symptoms Suspicion of testicular torsion before clinical assessment Exclusion Criteria: * Scrotal pain or symptoms caused by trauma Symptom duration \> 1 week History of testicular surgery Inability to provide informed consent (e.g., language barrier or cognitive limitation)

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Conditions

The condition(s) this trial relates to.

spermatic cord torsion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute scrotum Scrotal pain Testicular torsion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Linköping University Hospital, ED

    RECRUITING

    Linköping, Östergötland County, 58185, Sweden

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