New study aims to predict tumor changes during radiation using scans and blood tests
NCT ID NCT03491176
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether extra MRIs and blood tests can help doctors predict how head and neck tumors change during radiation therapy. Up to 100 people (80 patients and 20 healthy volunteers) will take part. The goal is to learn more about tumor growth and response, not to test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2017
- Expected to finish
-
Oct 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
MD Anderson Cancer Center
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Biopsy proven diagnosis of squamous cell carcinoma (SCC) of head and neck mucosa. Clinical evidence should be documented, and may consist of imaging, endoscopic evaluation, palpation, and should be sufficient to estimate the size of the primary for purposes of T staging * No distant metastases, based on routine staging workup * Consent for blood collection for biomarker analysis * No head and neck surgery of the primary tumor or lymph nodes except for incisional or excisional biopsies * Eastern Cooperative Oncology Group (ECOG) = 0, 1, or 2 * Dispositioned to curative intent radiotherapy * For females of child-bearing age, a negative pregnancy test Exclusion Criteria: * Previous radiation treatment for head and neck mucosal primary cancers within the past 5 years (i.e. oropharynx, nasopharynx, hypopharynx, larynx, and oral cavity) * Pregnant or breast-feeding females * Contraindications to magnetic resonance (MR) imaging (e.g. implanted metallic prostheses, defibrillators, or stimulators) * History of claustrophobia * Contraindications to gadolinium contrast (e.g. kidney dysfunction)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cutaneous squamous cell carcinoma of the head and neck are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a dental assistant keep cancer Patients' mouths healthier during radiation?
- Why do Non-Smokers get head and neck cancer? scientists probe tumor DNA
- Re-irradiation plus cetuximab targets head and neck tumors that return
- Sharper tumor maps: PET scans could tighten radiation beams
- Five days of radiation instead of weeks: a new test for head and neck cancer
- Can an online program ease the burden on cancer caregivers?