New hope for tough prostate cancer: drug combo trial launches
NCT ID NCT07206056
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 34 times
Summary
This study tests whether a new combination of two drugs (tulmimetostat and luxdegalutamide) can help men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy. About 188 men will take part across two phases: first to find the safest dose, then to compare the combo against usual care. The goal is to control the cancer and lower PSA levels, not to cure it.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Fred Hutchinson Cancer Research Center
RECRUITINGSeattle, Washington, 98109-1024, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mass General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Email: •••••@•••••
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Novartis Investigative Site
RECRUITINGSt Leonards, New South Wales, 2065, Australia
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Novartis Investigative Site
RECRUITINGMelbourne, Victoria, 3000, Australia
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Novartis Investigative Site
RECRUITINGLiverpool, 2170, Australia
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Novartis Investigative Site
RECRUITINGHalifax, Nova Scotia, B3H 2Y9, Canada
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Novartis Investigative Site
RECRUITINGBeijing, 100021, China
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Novartis Investigative Site
RECRUITINGHerlev, DK-2730, Denmark
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Novartis Investigative Site
RECRUITINGOdense C, 5000, Denmark
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Novartis Investigative Site
RECRUITINGVejle, DK-7100, Denmark
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Novartis Investigative Site
RECRUITINGBordeaux, 33076, France
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Novartis Investigative Site
RECRUITINGParis, 75015, France
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Novartis Investigative Site
RECRUITINGParis, 75231, France
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Novartis Investigative Site
RECRUITINGDüsseldorf, North Rhine-Westphalia, 40225, Germany
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Novartis Investigative Site
RECRUITINGMilan, MI, 20133, Italy
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Novartis Investigative Site
RECRUITINGPadova, PD, 35128, Italy
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Novartis Investigative Site
RECRUITINGOrbassano, TO, 10043, Italy
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Novartis Investigative Site
RECRUITINGKuching, Sarawak, 93586, Malaysia
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Novartis Investigative Site
RECRUITINGPoznan, 60-192, Poland
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Novartis Investigative Site
RECRUITINGSingapore, 119074, Singapore
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Novartis Investigative Site
RECRUITINGSingapore, S308433, Singapore
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Novartis Investigative Site
RECRUITINGSantiago Compostela, A Coruna, 15706, Spain
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Novartis Investigative Site
RECRUITINGL'Hospitalet de Llobregat, Barcelona, 08907, Spain
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Novartis Investigative Site
RECRUITINGMadrid, 28009, Spain
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Novartis Investigative Site
RECRUITINGMadrid, 28041, Spain
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Novartis Investigative Site
RECRUITINGSutton, Surrey, SM2 5PT, United Kingdom
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Novartis Investigative Site
RECRUITINGLondon, W1G 6AD, United Kingdom
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Sarah Cannon Research Institute
RECRUITINGDenver, Colorado, 80218, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Sarah Cannon Research Institute
RECRUITINGJacksonville, Florida, 32256, United States
Contact Email: •••••@•••••
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Wichita Urology Group PA
RECRUITINGWichita, Kansas, 67226, United States
Contact
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.