Could a simple nerve zap ease MS bladder troubles?
NCT ID NCT06341673
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a non-invasive nerve stimulation device placed on the ankle can reduce bladder symptoms like urgency and frequent urination in people with multiple sclerosis. 72 participants will be randomly assigned to receive either real or sham stimulation over several weeks. The goal is to see if this safe, at-home treatment improves bladder control and quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 72 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2024
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ambulatory (with or without assistive device) * Aged ≥18 years old * Able to understand spoken and written Arabic Language * Self-reported with at least one bladder storage symptom such as urinary frequency urinary urgency, nocturia, with or without urge urinary incontinence * Willing to give written informed consent * Able to understand how to complete the study outcome measures Exclusion Criteria: People with MS will be excluded if they have one or more of the following criteria at randomization: * Indwelling urethral catheter * Indwelling suprapubic catheter * Bladder malignancy * Diabetic mellitus * Pregnant women or plan to be pregnant during the study intervention * Recent pelvic related surgery \<1 year * Pacemaker or other metallic internal devices * Urinary tract infections (UTIs) during recruitment phase * Unable to understand the instructions relating to operating the unit * Having a bladder BOTOX-injection in the last 12-month
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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King Fahd Hospital of the University
RECRUITINGKhobar, Eastern Providence, Saudi Arabia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a nerve pacemaker that takes breaks still tame an overactive bladder?
- Ankle nerve zap may ease Kids' bladder troubles
- Can an antioxidant supplement ease bladder troubles in older women?
- App aims to ease bladder leakage in women without surgery
- What's it really like to live with overactive bladder? new study aims to find out