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New combo therapy aims to boost immune attack on eye cancer

NCT ID NCT07203391

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 28 times

Summary

This early-stage trial tests whether adding a new drug, roginolisib, to the standard treatment tebentafusp is safe and tolerable for people with advanced uveal melanoma, a rare eye cancer. The study enrolls 8 adults whose cancer has spread and who are already on tebentafusp. The goal is to find the best dose and see if the combination helps the immune system fight the cancer longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alfred Hospital

    NOT_YET_RECRUITING

    Melbourne, Victoria, Australia

    Contact

  • St Vincents Hospital

    RECRUITING

    Sydney, New South Wales, 2010, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.