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New root canal rinse could ease Post-Procedure pain

NCT ID NCT07435883

Symptom relief Sponsor: sara hosny mostafa Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new rinse called Triton during root canal treatment for dead teeth. It aims to see if it kills more bacteria and causes less pain afterward than the standard rinse. Thirty-six adults with infected lower molars will take part. The results could help dentists choose better rinses for patient comfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Triton irrigation solution
What this could lead to
If it works, this could lead to a more effective root canal irrigation method that reduces pain and infection after treatment.
What could go wrong
This is a small, early-stage trial with only 36 participants, so results may not apply to everyone. The new method may not be better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 36 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-45 years with no sex predilection * Medically free Patients with no systemic conditions that can affect post operative pain response. * Patients should not be taking any pain medications 24 hours before intervention * Positive patients' acceptance for participating in the study * Patient able to sign informed consent * Permanent mandibular molars diagnosis with pulpal necrosis with asymptomatic apical periodontitis. * Mandibular molars without any anatomical variations or severe curvatures with mesial roots configuration weine class 3 and a distal root with 2 distal canals Exclusion Criteria: * Medically compromised patients * Patients who have received antibiotic therapy within the last 2 weeks. * Pregnant or lactating women. * Patients with known allergy to any of the irrigants used. * Patients with swelling or acute peri-apical abscess or fistulous tract. * Teeth that have: * Wide or open apex . * Vital pulp tissue .

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pulp necrosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Oral and Dental Medicine , Future University in Egypt

    Cairo, New Cairo, 11835, Egypt

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