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Special stitches may fight infection after wisdom tooth surgery

NCT ID NCT07386366

Symptom relief Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 02, 2026 · Updated 4 times

Summary

This study tests whether stitches coated with an antibacterial agent (triclosan) help wounds heal better and reduce bacteria after removing impacted wisdom teeth. Fourteen adults will have both sides of their mouth stitched—one side with coated stitches and the other with standard stitches—and be followed for a week. The goal is to see if the coated stitches lead to faster healing and fewer germs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Triclosan-coated polyglactin 910 suture
What this could lead to
If it works, this could show that antibacterial stitches help wisdom tooth wounds heal better and with fewer bacteria, potentially reducing infection risk.
What could go wrong
This is a very small early trial with only 14 people, so results may not apply to everyone. The benefit may be small or not noticeable in real-world use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

15 people

The number who actually took part.

Started

Oct 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 35 years. * American Society of Anesthesiologists (ASA) physical status I or II. * Presence of two symmetric impacted mandibular third molars with the same level of difficulty according to the Pell-Gregory and Winter classification; the difference in angulation between the two third molars is no more than 15 degrees. * No use of topical or systemic antibiotics for at least 4 weeks before surgery. * Able and willing to provide written informed consent. * No active infection associated with the mandibular third molar at the time of enrollment. Exclusion Criteria: * Pregnant or breastfeeding. * Allergy to local anesthetic (2% lidocaine with 1:100,000 epinephrine) or any medications used in the study. * Radiographic findings suggestive of a tumor or cyst associated with the impacted mandibular third molar. * Participant withdraws consent or does not agree to continue participation. * Unable to attend scheduled follow-up visits. * Difference in surgical extraction time between the two procedures is 12 minutes or more. * Suture loss/loosening before completion of the final assessment time point.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Impacted mandibular third molar Postoperative wound healing

Contacts and locations

Locations

  • Specialized Dental Clinic, University of Medicine and Pharmacy at Ho Chi Minh City

    Ho Chi Minh City, Vietnam

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