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Appendicitis dilemma: survey reveals patient regret over treatment choice

NCT ID NCT05887414

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study surveyed over 2,500 appendicitis patients to understand their satisfaction and regret after choosing either surgery or antibiotics. Researchers aim to use this information to design decision-support tools that help future patients make choices aligned with their values. The study did not test any new treatment, but rather focused on improving the decision-making process.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better tools that help patients and doctors make more informed, personalized choices between surgery and antibiotics for appendicitis.
What could go wrong
This is a survey-based study, not a treatment trial. It measures patient feelings and preferences, not medical outcomes, so it won't directly change care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2,542 people

The number who actually took part.

Started

Oct 2022

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Any patient 18+ years old or older who has been diagnosed with appendicitis at a participating TRIAD clinical site after anticipated exclusion due to age, medical condition, or radiographic finding.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Any patient the clinical team feels is appropriate for considering either surgery or antibiotics for their initial appendicitis treatment Exclusion Criteria: * Pregnant patients * Immunocompromised patients * Patients with high complication risk of recurrent infections * Evidence of severe phlegmon or walled off abscess or free air on imaging * Septic shock * Diffuse peritonitis * Patients under 18 years old

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atrium Health

    Charlotte, North Carolina, 28204, United States

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Grady Health System / Morehouse School of Medicine

    Atlanta, Georgia, 30305, United States

  • Harborview Medical Center

    Seattle, Washington, 98104, United States

  • Kaiser Permanente Baldwin Park

    Baldwin Park, California, 90027, United States

  • Kaiser Permanente Los Angeles

    Los Angeles, California, 90027, United States

  • Kaiser Permanente Riverside

    Riverside, California, 92555, United States

  • Lyndon B Johnson- Harris Health

    Houston, Texas, 77026, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Michigan Medicine- University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • Northwest Hospital and Medical Center

    Seattle, Washington, 98133, United States

  • Northwestern Medicine

    Chicago, Illinois, 60611, United States

  • Texas Tech University

    Lubbock, Texas, 79430, United States

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77026, United States

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

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