Appendicitis dilemma: survey reveals patient regret over treatment choice
NCT ID NCT05887414
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study surveyed over 2,500 appendicitis patients to understand their satisfaction and regret after choosing either surgery or antibiotics. Researchers aim to use this information to design decision-support tools that help future patients make choices aligned with their values. The study did not test any new treatment, but rather focused on improving the decision-making process.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better tools that help patients and doctors make more informed, personalized choices between surgery and antibiotics for appendicitis.
- What could go wrong
- This is a survey-based study, not a treatment trial. It measures patient feelings and preferences, not medical outcomes, so it won't directly change care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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2,542 people
The number who actually took part.
- Started
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Oct 2022
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Any patient 18+ years old or older who has been diagnosed with appendicitis at a participating TRIAD clinical site after anticipated exclusion due to age, medical condition, or radiographic finding.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Any patient the clinical team feels is appropriate for considering either surgery or antibiotics for their initial appendicitis treatment Exclusion Criteria: * Pregnant patients * Immunocompromised patients * Patients with high complication risk of recurrent infections * Evidence of severe phlegmon or walled off abscess or free air on imaging * Septic shock * Diffuse peritonitis * Patients under 18 years old
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Atrium Health
Charlotte, North Carolina, 28204, United States
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Boston Medical Center
Boston, Massachusetts, 02118, United States
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Columbia University Medical Center
New York, New York, 10032, United States
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Grady Health System / Morehouse School of Medicine
Atlanta, Georgia, 30305, United States
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Harborview Medical Center
Seattle, Washington, 98104, United States
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Kaiser Permanente Baldwin Park
Baldwin Park, California, 90027, United States
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Kaiser Permanente Los Angeles
Los Angeles, California, 90027, United States
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Kaiser Permanente Riverside
Riverside, California, 92555, United States
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Lyndon B Johnson- Harris Health
Houston, Texas, 77026, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Michigan Medicine- University of Michigan
Ann Arbor, Michigan, 48109, United States
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Northwest Hospital and Medical Center
Seattle, Washington, 98133, United States
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Northwestern Medicine
Chicago, Illinois, 60611, United States
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Texas Tech University
Lubbock, Texas, 79430, United States
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The University of Texas Health Science Center at Houston
Houston, Texas, 77026, United States
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University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
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University of Washington Medical Center
Seattle, Washington, 98195, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Scoring system may spare appendicitis patients unnecessary scans and surgery
- Smartphone Follow-Up could replace hospital stays after common surgeries
- New Wound-Cleaning method may let surgeons close incisions right away after severe appendicitis
- Could less be more? shorter antibiotic course after appendix surgery put to the test
- Scientists create detailed map of appendix cells
- Cartoons and games beat Pre-Surgery jitters in kids