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Head-Down tilt may stop blood pressure crash during anesthesia in seniors

NCT ID NCT06968091

Symptom relief Sponsor: Zhejiang Cancer Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether tilting elderly patients head-down at a 10-degree angle during the start of anesthesia could prevent dangerously low blood pressure. Researchers compared this position to lying flat in 168 patients aged 65-90 having abdominal surgery. The main goal was to see if the head-down tilt reduced the time blood pressure stayed too low in the first 15 minutes after anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Trendelenburg positioning (tilting the body head-down at a 10-degree angle)
What this could lead to
If effective, this simple head-down tilt could become a standard, low-cost way to prevent dangerous drops in blood pressure when elderly patients are put to sleep for surgery.
What could go wrong
This is a completed, moderate-sized trial, but the effect may be modest or not apply to all elderly patients. The head-down position also has risks (e.g., breathing or brain pressure issues) that limit who can use it.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

168 people

The number who actually took part.

Started

May 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients aged 65-90 years * scheduled for abdominal surgery with general anesthesia * expected to have continuous radial arterial pressure monitoring * American Society of Anesthesiologists (ASA) physical status I to III Exclusion Criteria: * contraindications or failure of radial arterial catheterization * expected possible difficult airway * non-sinus rhythm * increased intracranial pressure * patients at high risk of regurgitation or aspiration * inability to provide consent

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Conditions

The condition(s) this trial relates to.

hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypotension on induction Old age

Contacts and locations

Locations

  • Zhejiang cancer hospital

    Hangzhou, Zhejiang, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.